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Fakultät Bio- und Chemieingenieurwesen
© CBE​/​BCI

 

New paper in Advanced Science on the identification of Trypstatin as an inhibitor of the TMPRSS2 protease and related proteases at nanomolar ranges. TMPRSS2 is a key element for the infection of SARS-CoV-2. Trypstatin showed a higher binding affinity than other protease inhibitors with anti-SARS-CoV-2 activity, like anti-thrombin and anti-trypsin.

Congratulations Yasser!

 https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202506430